Publications by authors named "J Del Pozo"
This longitudinal study delves into the impact of the COVID-19 pandemic on the utilization of digital tools in education, particularly focusing on the transition of classrooms into digital spaces. Three years after the lockdown, results from 144 primary and secondary teachers who also participated in a questionnaire during the lockdown indicate an expected decline in the frequency of using digital resources, particularly in attitude and assessment-related activities. Furthermore, activities centred around verbal and procedural learning continue to be teacher-centred.
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- - Multicellular organisms, like plants, use specialized barriers in their cells to interact with the environment, with the endodermal Casparian strip (CS) being a key feature in plant roots.
- - In tomato plants, researchers found that instead of forming a CS, the exodermis creates a polar lignin cap (PLC) that has a similar protective function but is regulated differently at the genetic level.
- - While both the exodermis and endodermis create barriers that limit mineral ion uptake, the exodermal PLC can't fully replace the endodermal CS, suggesting that these unique lignin structures play important roles in how roots respond to environmental challenges.
Background: Pneumocystis jirovecii pneumonia (PcP) is an opportunistic infection for which the standard of care is co-trimoxazole. However, safety concerns and intolerance may compromise its utility.
Objectives: To evaluate the safety and efficacy of the combination of echinocandins and clindamycin to treat PcP.
Efficacy of extended infusion of β-lactam antibiotics for the treatment of febrile neutropenia in haematologic patients (BEATLE): a randomized, multicentre, open-label, superiority clinical trial.
Clin Microbiol Infect
October 2024
Article Synopsis
- The study aimed to evaluate whether extended infusions (EI) of β-lactam antibiotics are more effective than intermittent infusions (II) in treating febrile neutropenia, a condition common in patients receiving chemotherapy and stem cell transplants.
- In a clinical trial involving 150 patients from four Spanish hospitals, those receiving EI experienced a slightly lower success rate at day 5 compared to those on II (50.6% vs. 63.0%), although not statistically significant.
- The research concluded that routine use of EI for β-lactams in this patient group is not supported, suggesting the need for further studies to address the diverse clinical aspects of febrile neutropenia.
Article Synopsis
- Systemic mastocytosis (SM) is a complex disease linked to abnormal mast cells that release mediators affecting the immune environment.
- The study aimed to explore the blood profiles of B-cells, plasma cells, and antibody types in 108 SM patients compared to healthy individuals.
- Results showed increased immature B-cells and elevated IgM and IgD levels in SM patients, alongside decreased plasma cells across various IgH types, with unique immune patterns based on the SM subtype.