Publications by authors named "J De-la-Cruz-Bertolo"

Introduction: the stability of total parenteral nutrition admixtures for neonates (TPNAn) has been questioned in relation to the interaction between calcium and fish oil emulsions. Aim: the aim of this study was to check the stability (particle size < 1 µm) of different individualized TPNAn prepared with fish-oil emulsion and containing calcium at concentrations ranging from 10 to 20 mmol/L. Methods: admixtures analyzed: twelve different formulations with SMOFlipid® 20 % (conserved for 24 h and for 96 h), three formulations with Lipoplus® 20 % (conserved for 96 h) and three formulations with SMOFlipid® 20 % with Multi-12K1® Pediatric (conserved for 96 h).

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Aim: The architecture of neonatal units plays a key role in developmental strategies and preterm outcomes. The aim was to evaluate the design of Spanish neonatal units and its impact on the participation of parents in neonatal care.

Methods: A web-based survey was sent to all level III Spanish neonatal units, including questions about hospital data, architectural design, facilities and family participation.

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Article Synopsis
  • - The LEONE-HT study investigates the poor heart transplant (HT) survival rates and the role of anti-HLA antibodies, which may cause cardiac allograft dysfunction in patients receiving heart transplants.
  • - It involves a cohort of HT patients, comparing those with positive anti-HLA antibodies to those without, utilizing advanced assessment methods like imaging and immunological analyses to understand the extent of myocardial damage.
  • - Ethical standards for the study are met, adhering to global guidelines, and findings will be shared through patient associations and registered on clinicaltrials.gov for transparency.
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Unlabelled: Antibiotic burden is a critical issue in neonatal intensive care units (NICU) and antibiotic use is considered a quality indicator of neonatal care. Our aim was to optimize antibiotic use through a quality improvement (QI) initiative that included revision of departmental protocols and implementation of a surveillance system based on process indicators.

Methods: This is descriptive study of a cohort of all very low birth weight (VLBW) infants admitted to the NICU from 2014 to 2019.

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  • A study examined cardiorespiratory events (CREs) in healthy term newborns during early skin-to-skin contact after birth, finding that 66.5% experienced at least one CRE, marked by low oxygen saturation or abnormal heart rates.
  • Factors increasing the risk of CREs included maternal age of 35 or older, being a first-time mother, a gestational BMI over 25, and births occurring at night.
  • Identifying these risk factors allows healthcare providers to monitor at-risk newborns more closely during early skin-to-skin contact, improving care and outcomes.
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