Publications by authors named "J De Jong"
Dementia probably due to Alzheimer's disease is a progressive condition that manifests in cognitive decline and impairs patients' daily life. Affected patients show great heterogeneity in their symptomatic progression, which hampers the identification of efficacious treatments in clinical trials. Using artificial intelligence approaches to enable clinical enrichment trials serves a promising avenue to identify treatments.
View Article and Find Full Text PDFVarious countries have implemented a choice-based health insurance system. For such systems to function as intended, it is crucial that all citizens have the opportunity to make well-informed decisions with regard to their health insurance policy. There is, however, ample research evidence to suggest that many citizens may lack the required skills to do so, thus increasing the likelihood of suboptimal insurance choices and incurring unexpected costs.
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- The study aimed to analyze the impact of race, sex, comorbidities, and Medicaid status on health outcomes for patients with hard-to-heal venous leg ulcers (VLUs), comparing Medicare-only beneficiaries to Medicare/Medicaid dual-enrollees from October 2015 to October 2019.
- Using Medicare claims data, the research focused on treatment methods, demographic comparisons, and quantified outcomes like ulcer closure time and quality of life metrics, finding notable differences between the two groups.
- Results showed that dual-enrollees had a higher burden of comorbidities, greater representation from minority backgrounds, and significantly increased rates of emergency visits and cellulitis compared to Medicare-only enrollees, with early use of certain
Frailty is characterized by loss of physical function and is preferably diagnosed at an early stage (e.g., during pre-frailty).
View Article and Find Full Text PDFInappropriate Therapy and Shock Rates Between the Subcutaneous and Transvenous Implantable Cardiac Defibrillator: A Secondary Analysis of the PRAETORIAN Trial.
Circ Arrhythm Electrophysiol
December 2024
Article Synopsis
- Inappropriate therapy (IAT) is a significant issue associated with implantable cardiac defibrillator (ICD) therapy, particularly highlighted in early subcutaneous ICD (S-ICD) studies which showed high rates of inappropriate shocks (IAS).
- The PRAETORIAN trial, an international study with 849 patients, found no major differences in IAT and IAS rates between S-ICD and transvenous ICD (TV-ICD) groups, as both groups had similar cumulative incidences.
- Key predictors for IAT varied between the two groups, with TV-ICD patients experiencing IAT mainly from supraventricular tachycardias, while S-ICD patients faced issues from cardiac oversensing