Publications by authors named "J David Krause"

IgA-coated fractions of the intestinal microbiota of Crohn's disease (CD) patients have been shown to contain taxa that hallmark the compositional dysbiosis in CD microbiomes. However, the correlation between other cellular properties of intestinal bacteria and disease has not been explored further, especially for features that are not directly driven by the host immune-system, e.g.

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After a long-distance migration, Avars with Eastern Asian ancestry arrived in Eastern Central Europe in 567 to 568 CE and encountered groups with very different European ancestry. We used ancient genome-wide data of 722 individuals and fine-grained interdisciplinary analysis of large seventh- to eighth-century CE neighbouring cemeteries south of Vienna (Austria) to address the centuries-long impact of this encounter. We found that even 200 years after immigration, the ancestry at one site (Leobersdorf) remained dominantly East Asian-like, whereas the other site (Mödling) shows local, European-like ancestry.

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  • The discharge of calved ice and subglacial runoff in Disko Bay, home to Sermeq Kujalleq glacier, is expected to influence marine biogeochemistry, particularly affecting the marine silica cycle due to elevated dissolved silica (dSi) from glaciers.
  • The study analyzes silica dynamics in various regions around Disko Bay, finding that land-terminating glaciers show conservative dSi patterns, whereas marine-terminating glaciers significantly alter nutrient distribution through subglacial discharge plumes.
  • The research quantifies contributions to dSi enrichment, highlighting that a large fraction comes from saline water entrainment, with minor contributions from icebergs and amorphous silica dissolution, ultimately adding a small but significant dSi flux to the environment.
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  • The study aimed to see if a mindfulness-based intervention (MBI) helps adolescents cope better with chronic stress compared to just mentoring alone.
  • Researchers worked with 81 adolescents, collecting data on their mindfulness and emotion regulation through daily assessments before, during, and after the intervention.
  • Results showed that MBI combined with mentoring slightly improved how adolescents managed stress, suggesting that mindfulness training could help buffer against the negative effects of stress in their daily lives.
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  • The study investigates how the Lapland longspur, a wild arctic-breeding bird, reacts to extreme weather events and what coping strategies it employs.
  • The researchers analyze gene expression changes using RNA-seq to see how environmental stressors like a cold spring and a severe storm impact the bird's stress response, reproductive behaviors, and metabolism.
  • Key findings include the significant up-regulation of the FKBP5 gene in the hypothalamus, which contributes to understanding how the bird adapts to changing climates and provides resources for future genomic studies.
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