A trial of positive airway pressure for the treatment of sleep apnea in pregnancy.

Background: The pathophysiology of obstructive sleep apnea in pregnancy remains poorly understood and studies examining the effect of treatment with positive airway pressure on pregnancy have been limited.

Objective: This study aimed to perform a randomized controlled trial of positive airway pressure treatment for obstructive sleep apnea in pregnancy.

Study Design: Participants with a body mass index ≥30 kg/m underwent polysomnography at 14 to 20 weeks' gestation (visit 1) and those with obstructive sleep apnea (apnea-hypopnea index ≥5 but <50) were enrolled.

A trait of mind: stability and robustness of sleep across sleep opportunity manipulations during simulated military operational stress.

Study Objectives: Within-subject stability of certain sleep features across multiple nights is thought to reflect the trait-like behavior of sleep. However, to be considered a trait, a parameter must be both stable and robust. Here, we examined the stability (i.

Identification of Veterans With PTSD Based on EEG Features Collected During Sleep.

Previously, we identified sleep-electroencephalography (EEG) spectral power and synchrony features that differed significantly at a population-average level between subjects with and without posttraumatic stress disorder (PTSD). Here, we aimed to examine the extent to which a combination of such features could objectively identify individual subjects with PTSD. We analyzed EEG data recorded from 78 combat-exposed Veteran men with ( = 31) and without ( = 47) PTSD during two consecutive nights of sleep.

Increased oscillatory frequency of sleep spindles in combat-exposed veteran men with post-traumatic stress disorder.

Study Objectives: Sleep disturbances are core symptoms of post-traumatic stress disorder (PTSD), but reliable sleep markers of PTSD have yet to be identified. Sleep spindles are important brain waves associated with sleep protection and sleep-dependent memory consolidation. The present study tested whether sleep spindles are altered in individuals with PTSD and whether the findings are reproducible across nights and subsamples of the study.

Alterations in sleep electroencephalography synchrony in combat-exposed veterans with post-traumatic stress disorder.

Study Objectives: We assessed whether the synchrony between brain regions, analyzed using electroencephalography (EEG) signals recorded during sleep, is altered in subjects with post-traumatic stress disorder (PTSD) and whether the results are reproducible across consecutive nights and subpopulations of the study.

Methods: A total of 78 combat-exposed veteran men with (n = 31) and without (n = 47) PTSD completed two consecutive laboratory nights of high-density EEG recordings. We computed a measure of synchrony for each EEG channel-pair across three sleep stages (rapid eye movement [REM] and non-REM stages 2 and 3) and six frequency bands.