Publications by authors named "J David Bradshaw"
Background Obstructive sleep apnea (OSA) is an intermittent hypoxia disorder associated with cognitive dysfunction, including learning and memory impairments. There is evidence that alterations in protease activity and neuronal activation as associated with cognitive dysfunction, are dependent on sex, and may be brain region-specific. However, the mechanisms mediating OSA-induced cognitive impairments are unclear.
View Article and Find Full Text PDFThis study investigated the effects of increasing previous resistance training (RT) weekly set volume by 30% (G30) and 60% (G60) on muscle hypertrophy and strength. Fifty-five resistance-trained men were randomly allocated to the experimental groups, while 29 completed the study, as follows: control group (CON): n=10, G30: n=10, and G60: n=9. Participants underwent a lower body RT program twice a week for eight weeks.
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- Veterans often experience hearing loss due to blast-induced injuries, particularly affecting the organ of Corti (OC) and hair cells in the cochlea, which are hard to measure experimentally.!* -
- A new 3D finite element model was developed to simulate how blast waves affect the OC, using components like sensory cells and surrounding fluid to more accurately assess potential injury locations.!* -
- The model showed significant structural strain where hair cells connect, suggesting a higher risk of damage from blasts, and it improved prediction accuracy by including interstitial fluid compared to previous models.!*
Objectives: To gather perspectives on childhood vaccination and vaccine hesitancy, the Saint Louis County Department of Public Health (DPH) surveyed parents seeking nonmedical exemptions, conducted focus groups of school nurses, and interviewed pediatricians.
Methods: We distributed exemption forms and voluntary questionnaires to parents in St Louis County who were seeking nonmedical exemptions for their school-aged children at any DPH clinic from August 2019 through December 2022. We conducted and recorded four 75- to 90-minute focus groups of 11 school nurses in groups of 2 or 3 nurses in September 2022.