Publications by authors named "J Damman"
Article Synopsis
- Nutritional care is seen as essential for improving outcomes in patients with chronic limb threatening ischemia (CLTI) due to their high risk of complications.
- A qualitative study involving focus groups revealed that healthcare professionals acknowledge the importance of nutritional care but often give it insufficient attention due to various barriers.
- Key challenges identified include knowledge gaps, a lack of routine incorporation of nutritional care, patient-related difficulties, and time constraints; however, enhancing scientific knowledge and organizational processes can help facilitate better nutritional care.
Article Synopsis
- Basal cell nevus syndrome (BCNS) can lead to multiple early-onset basal cell carcinomas (BCCs), with some cases linked to germline SUFU mutations, resulting in varying phenotypes, including multiple hereditary infundibulocystic basal cell carcinoma syndrome (MHIBCC).
- A study involving three patients with the MHIBCC phenotype identified new pathogenic SUFU variations, highlighting the different health risks associated with these mutations compared to other types of BCNS.
- It’s important for healthcare providers to recognize the MHIBCC phenotype to offer appropriate care, as the implications of germline SUFU mutations differ from those of other genetic syndromes like BCNS.
Imiquimod (IMQ; brand name Aldara®) is a registered topical agent that has been proven to induce local inflammation via the Toll-like receptor (TLR)7 pathway. The purpose of this study was to characterize TLR7-mediated inflammation following 7 days (168 h) of topical IMQ exposure in healthy volunteers, and to compare the effects of short exposure (48 h-72 h) with prolonged exposure (120 h-168 h). IMQ (100mg) was applied under occlusion to 5 different tape-stripped treatment sites on the back of 10 healthy participants for a maximum of 7 consecutive days.
View Article and Find Full Text PDFIntroduction: Vulvar lichen sclerosus (VLS) occurs in at least one in 900 girls. There is limited knowledge as to what extent the disease persists in adulthood and what the repercussions in adulthood may be. The aim of this study is to evaluate the long-term consequences of VLS diagnosed in childhood or adolescence.
View Article and Find Full Text PDFIncorrect and delayed diagnosis of vulvar high-grade squamous intraepithelial neoplasia (vHSIL) and lichen sclerosus (LS) increases malignant progression risks and negatively impacts prognosis and quality of life. There is a need to improve diagnosis and monitoring. Reflectance confocal microscopy is a non-invasive imaging tool that visualizes skin structures at cellular resolution.
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