Publications by authors named "J Daerr"
Early Outcomes of Pelvic Trauma Patients - Complications, ICU Stay and Treatment Concepts in Two ATLS Compliant Trauma Centers: Germany and Qatar.
Acta Chir Orthop Traumatol Cech
January 2022
Article Synopsis
- The study focuses on pelvic trauma in polytraumatized patients, highlighting its severe consequences such as significant bleeding and high risk of intra-abdominal injuries.
- Researchers compared two patient groups from Qatar and Germany to assess the impact of standardized treatment on early outcomes following pelvic fractures from 2013 to 2016.
- Findings indicate that while there were differences in demographics and injury severity between the groups, early outcomes like complication rates and blood transfusion needs showed comparable results, emphasizing the high complication risk associated with pelvic injuries.
An amino acid exchange (P209L) in the HSPB8 binding site of the human co-chaperone BAG3 gives rise to severe childhood cardiomyopathy. To phenocopy the disease in mice and gain insight into its mechanisms, we generated humanized transgenic mouse models. Expression of human BAG3-eGFP in mice caused Z-disc disintegration and formation of protein aggregates.
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