Functional connectivity development in the prenatal and neonatal stages measured by functional magnetic resonance imaging: A systematic review.

The prenatal and neonatal periods are two of the most important developmental stages of the human brain. It is therefore crucial to understand normal brain development and how early connections are established during these periods, in order to advance the state of knowledge on altered brain development and eventually identify early brain markers of neurodevelopmental disorders and diseases. In this systematic review (Prospero ID: CRD42024511365), we compiled resting state functional magnetic resonance imaging (fMRI) studies in healthy fetuses and neonates, in order to outline the main characteristics of typical development of the functional brain connectivity during the prenatal and neonatal periods.

General and Scalable Synthesis of 2-Aryl and 2-Alkyl Pyrimidines via an Electronically Tuned SAr Approach.

An efficient SAr approach for generating a wide array of 2-aryl and 2-alkyl pyrimidines in good to high yields was developed. This methodology does not require precious metal catalysts and is compatible with aryl, heteroaryl, and alkyl magnesium halides as nucleophiles. This process is scalable and performed at room temperature well below the temperature of the competing decomposition of the activated 2--butyl sulfonyl pyrimidine electrophile.

[Patients experiencing burnout : medico-social needs and resources].

There is a gap between the current service offer and the needs of people suffering from burnout. Actors in the field, from employers to prescribers, have a role to play in addressing the health needs of the target population, promoting existing services and facilitating their integrative collaboration. This is what a study evaluating the adequacy between the health needs of people experiencing burnout and the services offered to these patients from the point of view of key informants in the canton of Vaud has shown.

Metal-Free Electrochemical Reduction of Disulfides in an Undivided Cell under Mass Transfer Control.

Electroorganic synthesis is generally considered to be a green alternative to conventional redox reactions. Electrochemical reductions, however, are less advantageous in terms of sustainability, as sacrificial metal anodes are often employed. Divided cell operation avoids contact of the reduction products with the anode and allows for convenient solvent oxidation, enabling metal free greener electrochemical reductions.