Publications by authors named "J D Wallach"
Purpose Of Review: The rapid rise in incidence and prevalence of end-stage kidney disease (ESKD) over the past 50 years was matched by a drop-off in use of home dialysis and a proliferation of in-center hemodialysis across the United States. There is renewed interest in improving access to home dialysis modalities for patients with ESKD. The aim of this review is to update kidney care providers with clinical outcome data and new guidelines that promote patient-centered choices, and to address barriers to home dialysis uptake and continued use.
View Article and Find Full Text PDFObjective: In this pilot study a binaural pulse modulator was tested to see if it leads to a change in self-reported measures of distress. This binaural pulse modulator produces two frequencies that combine to create a binaural pulse to stimulate the nervous system through a differential auditory tone presentation and the response of the user can be adjusted to the appropriate target tone for effective treatment use. Each individual calibrated the binaural pulse to increase the level of emotion experienced while imagining an experience with a similar emotional valence or while engaged in a cognitive function while also listening to the sound.
View Article and Find Full Text PDFArticle Synopsis
- Non-Hodgkin lymphoma (NHL) is a prevalent type of blood cancer, and its causes remain largely unknown, though autoimmune diseases are suspected as potential risk factors.
- A study used Mendelian randomization to investigate the relationship between ten autoimmune diseases and NHL risk, utilizing data from various European ancestry cohorts.
- The results indicated that genetically predicted susceptibility to type 1 diabetes and sarcoidosis may lower NHL risk, while no significant association was found for the other eight autoimmune diseases; further research is needed to confirm these findings.
Article Synopsis
- Real-world evidence is gaining interest for assessing the efficacy and safety of treatments for substance use disorders (SUDs), but its feasibility as a substitute for clinical trials remains unclear.
- A study evaluated 272 clinical trials for SUDs registered on ClinicalTrials.gov to see if their data could be replicated using current insurance claims or electronic health records.
- Findings showed that while many trials had identifiable criteria, no trial met all the requirements for effective emulation using real-world data, highlighting limitations in available data sources.
Article Synopsis
- A systematic review was conducted to summarize quantitative bias analysis (QBA) methods for observational studies, focusing on their characteristics and range based on peer-reviewed articles.
- Out of over 10,000 records, 53 articles detailed 57 QBA methods, with a majority (93%) aimed at observational studies and relevant biases such as unmeasured confounding and misclassification.
- This review provides a valuable resource for future researchers to identify appropriate QBA methods to adjust for biases in summary-level epidemiologic data.