Publications by authors named "J D Savio"

A 31-year-old gentleman, hailing from West Bengal, a farmer by occupation, with no known prior comorbidities, presented with a history of multiple painful swellings over the abdomen, thorax (back and front), and suprapubic region of 6 months' duration. The swelling started in the abdomen and subsequently involved the thorax. It also progressively increased in size over the 6 months.

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Article Synopsis
  • A study analyzed mixed mould infections in patients with COVID-19-associated pulmonary mucormycosis (CAPM) to determine the prevalence of co-existing COVID-19-associated pulmonary aspergillosis (CAPA) and its impact on early mortality.
  • Among 105 patients with CAPM, 20% had mixed mould infections, and those with CAPA experienced significantly higher early mortality rates (42.9%) compared to those without (17.9%).
  • The findings suggest that co-existing CAPA worsens the prognosis for CAPM patients, highlighting the need for further research on mixed mould infections globally.
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Article Synopsis
  • The International Society for Human and Animal Mycology (ISHAM) has updated guidelines for managing allergic bronchopulmonary aspergillosis (ABPA) and allergic bronchopulmonary mycosis (ABPM) due to improvements in diagnostic and therapeutic methods.
  • An expert group utilized a modified Delphi method to reach a consensus on the recommendations, which include screening practices and diagnostic criteria for ABPA and ABPM in both adults and children.
  • Key recommendations include routine screening for fungal sensitization in specific patient groups, clear diagnostic criteria for ABPA and ABPM, and suggested treatments such as oral prednisolone or itraconazole for acute cases, while noting that asymptomatic ABPA patients do not require treatment.
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Background: Fungal infections are now a great public health threat, especially in those with underlying risk factors such as neutropenia, diabetes, high-dose steroid treatment, cancer chemotherapy, prolonged intensive care unit stay, and so on, which can lead to mycoses with higher mortality rates. The rates of these infections have been steadily increasing over the past 2 decades due to the increasing population of patients who are immunocompromised. However, the data regarding the exact burden of such infection are still not available from India.

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