Publications by authors named "J D Salciccioli"
Background: Cutaneous melanoma (CM) is the leading cause of skin cancer mortality with associated high healthcare costs. Up-to-date reporting of epidemiological trends for CM is required to project future trends, assess the burden of disease and aid evaluation of new diagnostic, therapeutic and preventative strategies.
Objectives: To describe the trends in CM mortality, incidence, mortality-to-incidence indices (MIIs) and disability-adjusted life years (DALYs) over the last three decades.
Asthma Biologics: Lung Function, Steroid-Dependence, and Exacerbations.
Immunol Allergy Clin North Am
November 2024
Article Synopsis
- The past two decades have seen significant advancements in asthma treatment with the development of targeted biologic therapies.
- There are currently six monoclonal antibodies designed to target specific inflammatory mediators involved in asthma, allowing for more personalized treatment options.
- These therapies include omalizumab (anti-IgE), mepolizumab and reslizumab (anti-IL-5), benralizumab (IL-5 receptor antagonist), dupilumab (IL-4 receptor antagonist), and tezepelumab (anti-thymic stromal lymphopoietin).
Objectives: Understanding the burden of disease of sepsis is essential for monitoring the effectiveness of international strategies to improve sepsis care. Our objective was to describe the multinational trend of sepsis-related mortality for the period 1985-2019 from the WHO Mortality Database.
Design: Retrospective analysis of the WHO Mortality Database.
Purpose Of Review: Mechanical chest compression devices are increasingly deployed during cardiopulmonary resuscitation. We discuss the data supporting the use of mechanical chest compression devices during cardiac arrest and provide an opinion about the future of the technology.
Recent Findings: Multiple randomized trials investigating the use of mechanical chest compression devices for out-of-hospital cardiac arrest have not demonstrated improved outcomes.
Background: The incidence of Pulmonary Hypertension (PH) and Pulmonary Arterial Hypertension (PAH) is believed to be on the rise and is associated with poor outcomes.
Methods: We extracted age-standardized mortality rates (ASMRs) for decedents ≥ 18 years of age from the World Health Organization Mortality Database, using International Classification of Diseases 10th edition codes for PH and PAH, covering the period from 2001 to 2019. The UK and European Union countries with at least 1,000,000 inhabitants and at least 75% of available data points over the study period were included.