Publications by authors named "J D Pohlmann"
Objective: This study assesses whether longitudinal quantitative pupillometry predicts neurological deterioration after large middle cerebral artery (MCA) stroke and determines how early changes are detectable.
Methods: This prospective, single-center observational cohort study included patients with large MCA stroke admitted to Boston Medical Center's intensive care unit (2019-2024). Associations between time-to-neurologic deterioration and quantitative pupillometry, including Neurological Pupil Index (NPi), were assessed using Cox proportional hazards models with time-dependent covariates adjusted for age, sex, and Alberta Stroke Program Early CT Score.
Numbers of European glass eels (Anguilla anguilla) monitored along the Atlantic and Mediterranean coasts of Europe currently serve as the main stock indicator in assessment of this critically endangered species. Spawning, however, takes place exclusively in the Sargasso Sea, several thousand kilometers away. The beginning of its complex lifecycle is characterized by a distant and lengthy larval drift, before the young-of-the-year reach the monitoring stations at the European coasts.
View Article and Find Full Text PDFArticle Synopsis
- The roundscale spearfish (Tetrapturus georgii) is not well-studied, leading to gaps in knowledge regarding its biology, ecology, and population status.
- Despite being morphologically distinct from similar species like the white marlin, misidentification complicates population assessments.
- This study presents the first documented records of a T. georgii egg and juvenile, offering new insights into its reproductive biology and early life stages, emphasizing the need for further research for effective conservation.
Malignant cerebral edema occurs when brain swelling displaces and compresses vital midline structures within the first week of a large middle cerebral artery stroke. Early interventions such as hyperosmolar therapy or surgical decompression may reverse secondary injury but must be administered judiciously. To optimize treatment and reduce secondary damage, clinicians need strategies to frequently and quantitatively assess the trajectory of edema using updated, relevant information.
View Article and Find Full Text PDFBackground: Life-threatening, space-occupying mass effect due to cerebral edema and/or hemorrhagic transformation is an early complication of patients with middle cerebral artery stroke. Little is known about longitudinal trajectories of laboratory and vital signs leading up to radiographic and clinical deterioration related to this mass effect.
Methods: We curated a retrospective data set of 635 patients with large middle cerebral artery stroke totaling 95,463 data points for 10 longitudinal covariates and 40 time-independent covariates.