Publications by authors named "J D Nobrega"
Background: Much of the research on sexual assault nurse examiners (SANEs) focuses on program outcomes rather than the individual experiences of SANEs. The present research therefore sought to examine the individual experiences of SANEs regarding trauma, support, training needs, and challenges.
Methods: A national sample of SANEs participated in an online survey.
Article Synopsis
- Kidney transplantation is critical for patients with end-stage renal disease in Portugal, which has a high organ donation rate due to an "opt-out" consent system.
- A survey of 427 fifth-year medical students revealed high awareness of donation laws and causes of kidney transplants, but notable gaps in knowledge about certain donation types and immunosuppressive drugs.
- Students expressed low satisfaction with their education on transplantation, indicating a need for improved curriculum and practical experience in medical training.
For years, cancer has been the second cause of death worldwide, preceded by cardiovascular diseases only. The number of research groups focusing on the discovery of new drugs to treat cancer is growing and the aim is to look for more effective compounds that cause less severe side effects and do not suffer from therapeutic resistance. The metal complexes cisplatin and carboplatin are widely used in the chemotherapeutic treatment of various types of cancer, including triple-negative breast cancer (TNBC).
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- The study investigates the role of C-type natriuretic peptide (CNP) and its receptor NPR2 in oocyte maturation and communication with cumulus cells in bovine COCs, following previous findings in other mammals.
- It finds that gonadotropins like FSH and LH reduce NPR3 mRNA levels in cumulus cells during maturation, while NPR2 levels remain unchanged, and inhibiting EGFR blocks this downregulation.
- Additionally, the research highlights that NPR3 activation can inhibit cumulus expansion, suggesting a complex interaction between CNP, NPR3, and gonadotropins affecting ovarian functions.*
Article Synopsis
- Cardiac arrest is a major global health issue, and sodium bicarbonate (SB) is often used during CPR to address metabolic acidosis, though its effectiveness is debated.
- A systematic review of studies from various medical databases found 12 relevant studies on SB's use in cardiac arrest, highlighting mixed results.
- Overall, while some studies hint at potential benefits in certain situations, the review concluded that SB is generally not recommended for standard cardiac arrest treatment, suggesting more research is needed to explore specific cases where it might be useful.