Comfort, consistency, and efficiency of garments with textile electrodes versus hydrogel electrodes for neuromuscular electrical stimulation in a randomized crossover trial.

The efficacy and comfort of neuromuscular electrical stimulation (NMES) largely depend on the type of electrodes used. Traditional self-adhesive hydrogel electrodes, while effective, pose limitations in terms of wearability, skin compatibility, and reusability. This randomized crossover trial investigates the performance of a specific textile electrode integrated into garments for NMES of lower extremities, focusing on their potential rehabilitative applications for patients with neurological disorders such as stroke, multiple sclerosis (MS), and spinal cord injury (SCI).

Modulating Charge Transfer Kinetics along Poly Adenine: Chemical Modifications, Temperature, and Conformational Effects.

The charge transfer (CT) reactions in nucleic acids are crucial for genome damage and repair and nanoelectronics using DNA as a molecular conductor. Previous experimental and theoretical works underlined the significance of nucleic acid structural dynamics on CT kinetics, requiring models that incorporate the dynamics of the nucleic acid, solvents, and counterions. Here, we investigated hole transfer kinetics in poly adenine single and double strands at various temperatures and the rate enhancement due to adenine-to-7-deazaadenine mutation by means of a QM/MM approach.