Interfacial Spin-Orbit-Coupling-Induced Strong Spin-to-Charge Conversion at an All-Oxide Ferromagnetic/Quasi-Two-Dimensional Electron Gas Interface.

Functional oxides and hybrid structures with interfacial spin-orbit coupling and the Rashba-Edelstein effect (REE) are promising materials systems for thermal tolerance spintronic device applications. Here, we demonstrate efficient spin-to-charge conversion through enhanced interfacial spin-orbit coupling at the all-oxide interface of LaCaMnO with quasi-two-dimensional (quasi-2D) SrTiO (LCMO/STO). The quasi-2D interface is generated via oxygen vacancies at the STO surface.

Selective State Space Models Outperform Transformers at Predicting RNA-Seq Read Coverage.

Transformers are the basis for many state-of-the-art machine learning tools, including those for predicting gene expression data from DNA sequence. The considerable time and cost of training transformer models has motivated development of alternative approaches inspired by ideas from the signal-processing literature, such as state-space models (Mamba), Fourier transforms (Hyena), and wavelet transforms (MultiResNet). To evaluate these methods as potential replacements (or complements) for attention, we developed a software library bilby, implemented using Python and Jax/Flax, providing convolutional, attention, bidirectional Hyena, bidirectional Mamba, and striped-architecture models for supervised multi-task learning in functional genomics.

Comparative Patho-Genomics of Serovar Enteritidis Reveal Potential Host-Specific Virulence Factors.

serovar Enteritidis ( Enteritidis) is one of the most common causes of bacterial foodborne infections worldwide. It has an extensive host range, including birds and humans, making it one of the most adaptable serovars. This study aims to define the virulence gene profile of Enteritidis and identify genes critical to its host specificity.

Left atrial mechanics in youth with chronic kidney disease and similarly aged healthy controls.

Background: In adults with chronic kidney disease (CKD), abnormal left atrial reservoir strain (LASr) is an early, yet clinically significant, indicator of myocardial dysfunction. However, left atrial mechanics are understudied in youth with CKD. The objective of this study was to assess left atrial strain function in youth with CKD and similarly aged, healthy controls.

Implementation of patient-reported outcome dashboards within the electronic health record to support shared decision-making in serious chronic illness.

Background: Attending to patient-reported outcomes (PROs) using data visualisation dashboards could enhance shared decision-making (SDM) and care delivery for serious chronic illnesses. However, few studies have evaluated real-world strategies and resulting implementation outcomes of PRO dashboards.

Method: From June 2020 to January 2022, we implemented an electronic health record (EHR)-integrated PRO dashboard for advanced cancer and chronic kidney disease.