Publications by authors named "J D Lakhani"

Death is no stranger to the neonatal intensive care unit (NICU). Extreme prematurity, congenital abnormalities, and other complexities can turn what was hoped to be a very exciting moment in a family's life into one of despair and grief. There are many infants that not only do not survive but also have a medicalized death necessitating complex decision-making, weighing quality versus duration of life.

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Background: Though the treatment of uncomplicated varicose vein (UVV) might prevent late complications such as skin change or ulceration, but, there are limited studies available to justify this concept. Yoga and Naturopathy being a proficient tool in managing non communicable diseases including many cardiovascular diseases; no attempt was made to study its potential effect in Varicose Vein diseases.

Objective: The present study aims to study the combination of Yoga and Naturopathy in uncomplicated varicose vein patients.

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Spleen has been found to be the earliest organ involved in sickle cell disease (SCD) patients with variable manifestations in different geographical regions. It usually undergoes autosplenectomy by adolescence but in countries like India, the course of the disease and splenic manifestations are different. And here we aim to study these differences and the relationship between spleen size and fetal hemoglobin (HbF) and various splenic complications in our patients with sickle cell disease.

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Background: Parental bereavement after the death of an infant in a neonatal intensive care unit (NICU) is a complex and nuanced experience. Support from healthcare practitioners can have a significant impact on bereavement experiences in the short- and long-term. Although several studies exist exploring parental perceptions of their experience of loss and bereavement, there has not been a recent review of beneficial practices and common themes in the current literature.

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Article Synopsis
  • TEAD and YAP/TAZ are important proteins that help control gene activity and are linked to some types of cancer, making them good targets for new drugs.
  • Scientists faced challenges in designing small drugs to affect TEAD, but they found a way to create a special drug called MYF-03-69 that binds to TEAD effectively and stops cancer growth.
  • Further development led to a stronger version of the drug, MYF-03-176, which was successful in stopping tumors in mice and shows promise for treating cancers related to TEAD and YAP.
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