Publications by authors named "J D Kephart"
Black men suffer disproportionately from prostate cancer (PCa) compared to men of other races and ethnicities. Comparing the molecular landscape of PCa among Black and White patients has the potential to identify targets for development of new precision medicine interventions. Herein, we conducted transcriptomic analysis of prostate tumors and paired tumor-adjacent normals from self-reported Black and White PCa patients and estimated patient genetic ancestry.
View Article and Find Full Text PDFThis study investigates the electronic interactions and charge redistribution at the dopant-support interface using a Cu/CoSe cluster construct. Specifically, the redox cluster series [CuCoSeL] ([-Cu]; = 0, -1, -2, -3; L = PhPNTol, Ph = phenyl, Tol = -tolyl) spanning four distinct oxidation states is synthesized and characterized using a multitude of techniques, including multinuclear NMR, UV-vis, XANES, and X-ray crystallography. Structural investigations indicate that the clusters are isostructural and chiral, adopting a pseudo- symmetry.
View Article and Find Full Text PDFArticle Synopsis
- - Heatwaves in Latin America are expected to become more frequent, longer, and more intense by mid-century, with even greater increases under the high emissions scenario (RCP8.5) compared to the low emissions scenario (RCP2.6).
- - The frequency of heatwaves may double across most of Latin America, leading to a significant increase in population exposure to extreme heat, projected to rise by three to ten times in Central and South America.
- - Following a low emissions pathway (RCP2.6) could significantly reduce heatwave exposure—by 57% in Central America and 50% in South America—emphasizing the need for emissions control and sustainable practices to mitigate climate change impacts. *
Climate hazards threaten the health and wellbeing of people living in urban areas. This study characterized reported climate hazards, adaptation action, and barriers to adaptation in 124 Latin American cities, and associations of climate hazards with urban social and built environment characteristics. We examined cities that responded to a global environmental disclosure system and that were included in the Urban Health in Latin America (SALURBAL) Project database.
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- Climate change is causing more flooding, especially in cities in Latin American countries where people have less money.
- The study looked at 276 cities and found that neighborhoods with lower education levels have a lot more flooding.
- It's really important for leaders to focus on helping these neighborhoods deal with floods because people there are at higher risk.