Publications by authors named "J D Ivory"

This descriptive, cross-sectional study aimed to identify whether having a chronic leg ulcer (CLU), in addition to diabetes, contributed to frailty in individuals ≥65 years old. It also explored the associations between frailty, pre-frailty and other factors. 125 participants aged ≥65 attending outpatient clinics in Ireland were categorised into three groups: (1) diabetes-only and no CLU, (2) CLU-only and no diabetes, and (3) diabetes and CLU.

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Article Synopsis
  • - Parents with BRCA1/2 mutations face challenges in sharing their genetic risk information with their minor children, including uncertainty about timing, content, and approach.
  • - A scoping review analyzed 22 articles exploring strategies for parents and healthcare professionals regarding these conversations but found a lack of support interventions for parents during the disclosure process.
  • - The study highlights a need for healthcare professionals to create effective communication strategies and emphasizes the necessity for further research on how families navigate sharing genetic information.
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Article Synopsis
  • The scoping review aims to identify and map the different methods used to assess wound odour, a significant concern for patients and healthcare providers.
  • Wound odour is considered one of the most distressing symptoms, and the lack of a standard assessment method complicates clinical trials and meta-analyses.
  • The review will follow specific guidelines, present findings in a narrative format, and ultimately help establish a consensus on the best practices for assessing wound odour through a follow-up Delphi study.*
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Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus, defined as infection, ulceration and/or destruction of deep tissues and/or peripheral artery disease in the lower extremities. Efficient cleansing is essential for the treatment of wounds, as it removes debris and necrotic tissue and decreases the burden of wound-colonizing microorganisms. The objective was to conduct a systematic review of the literature to investigate the effects of wound cleansing agents commonly used in DFU care, compared to the use of normal saline for DFU management.

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Purpose: Genomic tests, such as the Oncotype Dx 21-gene and Prosigna risk of recurrence (ROR-P) assay, are commonly used for breast cancer prognostication. Emerging data suggest variability between assays, but this has not been compared in diverse populations.

Materials And Methods: RNA sequencing was performed on 647 previously untreated stage I-III estrogen receptor-positive/human epidermal growth factor receptor 2-negative tumors in the Carolina Breast Cancer Study, which oversampled Black and younger women (age <50 years at diagnosis), using research versions of two common RNA-based prognostic assays: ROR-P and the 21-gene recurrence score (RS).

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