Evaluating the Impact of Changes in AI-derived Case Scores over Time on Digital Breast Tomosynthesis Screening Outcomes.

Purpose To evaluate the change in DBT-AI (digital breast tomosynthesis-artificial intelligence) case scores over sequential screens. Materials and Methods This retrospective review included 21,108 female patients (mean age, 58.1 ± [SD] 11.

Detecting early stages of Alzheimer's disease using a web-based cognitive battery.

Portable and efficient cognitive screening measures are needed to address the growing need for effective early detection of Alzheimer's disease. The Neurotrack Cognitive Battery (NCB) offers an appealing, web-based application that may be sensitive to early cognitive changes associated with Alzheimer's disease. The NCB contains measures that were conceptually derived from animal lesion studies.

Characterization of upper esophageal sphincter pressures relative to vocal acoustics.

Strength of vocal fold adduction has been hypothesized to be a critical factor influencing vocal acoustics but has been difficult to measure directly during phonation. Recent work has suggested that upper esophageal sphincter (UES) pressure, which can be easily assessed, increases with stronger vocal fold adduction, raising the possibility that UES pressure might indirectly reflect vocal fold adduction strength. However, concurrent UES pressure and vocal acoustics have not previously been examined across different vocal tasks.

Laryngeal Vibrotactile Stimulation Is Feasible, Acceptable To People With Unexplained Chronic Cough.

Objectives: Unexplained chronic cough (UCC) is common and has significant impacts on quality of life. Ongoing cough can sensitize the larynx, increasing the urge to cough and perpetuating the cycle of chronic cough. Vibrotactile stimulation (VTS) of the larynx is a noninvasive stimulation technique that can modulate laryngeal somatosensory and motor activity.

Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment.

Introduction: Mild cognitive impairment (MCI) is a prodromal stage of dementia. Understanding the mechanistic changes from healthy aging to MCI is critical for comprehending disease progression and enabling preventative intervention.

Methods: Patients with MCI and age-matched controls (CN) were administered cognitive tasks during functional near-infrared spectroscopy (fNIRS) recording, and changes in plasma levels of extracellular vesicles (EVs) were assessed using small-particle flow cytometry.