Publications by authors named "J D Gonzalez-Ramirez"

Pulpitis, an inflammation of the dental pulp, is generated by bacterial invasion through different ways as caries. In the establishment and development of this disease, different biological processes are involved. Long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) are transcripts with regulatory capacity participating in different biological functions and have been implicated in different diseases.

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Article Synopsis
  • The study aimed to assess how nuclear orphan receptors are related to the development of Uterine Cervical Cancer (UCC), specifically focusing on the impact of human papilloma virus on cervical changes.
  • Researchers measured the expression of three orphan receptors (NR4A1, NR4A2, NR4A3) using RT-PCR in biopsies from 45 patients with varying cervical conditions.
  • The findings indicated specific expression patterns of these receptors linked to different premalignant lesions, suggesting their potential role in UCC progression.
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Potyvirus diseases are one of the main challenges facing the production of yam ( spp.). The objective of this study was to identify the potyviruses present in the spp.

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Dermatologic disorders, affecting the integumentary system, involve diverse molecular mechanisms such as cell proliferation, apoptosis, inflammation and immune responses. Long noncoding RNAs, particularly Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1), are crucial regulators of gene expression. MALAT1 influences inflammatory responses, immune cell function and signaling pathways, impacting various physiological and pathological processes, including dermatologic disorders.

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Keratinocytes, the principal epidermal cells, play a vital role in maintaining the structural integrity and functionality of the skin. Beyond their protective role, keratinocytes are key contributors to the process of wound healing, as they migrate to injury sites, proliferate, and generate new layers of epidermis, facilitating tissue repair and remodeling. Moreover, keratinocytes actively participate in the skin's immune responses, expressing pattern recognition receptors (PRRs) to detect microbial components and interact with immune cells to influence adaptive immunity.

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