Publications by authors named "J D Giesy"
Background: subsp. (Maire) Figuerola (SBm) is a plant endemic to Morocco and is one of the less studied species of Salvia. Herbal therapy is becoming more and more popular, especially in underdeveloped nations where access to medicinal herbs is affordable.
View Article and Find Full Text PDFMethanol poisoning can occur through consumption of methanol-containing alcohols, especially in areas where production, distribution, sale and consumption of alcohol is lawfully prohibited. Due to its toxic potency, determination of methanol in alcoholic solutions is important. The aim of the present study was to develop a rapid, simple and inexpensive method for quantification of methanol in alcoholic solutions that uses minimal equipment available in most laboratories.
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- Bioactive compounds, particularly essential oils (EOs) and their terpenoids, have been shown to effectively accelerate wound healing (WH) by providing a safe alternative to traditional treatments.
- Studies have identified 38 species of EOs from various families, with the Lamiaceae family being the most represented, highlighting their roles as anti-inflammatory, antioxidant, and antimicrobial agents, and facilitating cellular repair and proliferation through various biological mechanisms.
- Recent advancements in nanotechnology have enhanced the development of drug delivery systems (DDS) that incorporate EOs, but challenges remain in translating these innovations into practical clinical applications for wound management.
Ligand-specific binding interactions of xenobiotics with receptor proteins form the basis of cytotoxicity-based hazard assessment. Computational approaches enable predictive hazard assessment for a large number of chemicals in a high-throughput manner, minimizing the use of animal testing. However, in silico models for predicting mechanisms of toxic actions and potencies are difficult to develop because toxicity datasets or comprehensive understanding of the complicated kinetic process of ligand-receptor interactions are needed for model development.
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- This review explores the link between climate change and the rise in Valley Fever (VF), a serious fungal infection caused by Coccidioides fungi, which has become more prevalent due to increased natural disaster events like dust storms and droughts.
- Over a span of two decades, cases of VF in California have surged fivefold, with annual deaths averaging around 200 in the U.S., indicating that climate change could lead to even higher incidence rates and fatalities.
- The study emphasizes the need for more research on how shifting weather patterns affect VF's spread and discusses potential areas impacted, especially in endemic regions like California, Arizona, and surrounding southern states.