Publications by authors named "J D Doublet"
Malignant hypertension (MHT) crisis triggers widespread microvascular damage, particularly in the brain. Despite recent MRI evidence highlighting acute cerebral injuries during MHT crises, follow-up data remain scarce. This study seeks to fill this gap by exploring how brain MRI markers evolve following acute MHT crisis management.
View Article and Find Full Text PDFBackground: Cardiac troponin is the pivotal biomarker of myocardial injury, playing a central role in the diagnosis of acute coronary syndrome and various clinical situations. Nevertheless, challenges arise when patients exhibit elevated cardiac troponin levels in the absence of evident cardiac origin, as evidenced by extensive cardiac exploration, which suggests the presence of an interfering factor. Despite the high performance of high-sensitive cardiac troponin immunoassays, these tests remain susceptible to interferences that may lead to false-positives.
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- Laparoscopic adrenalectomy (LA) is a minimally invasive surgery that has become the preferred treatment for adrenal diseases, but its use in outpatient settings is still not widespread.
- A study reviewed 76 LA procedures for primary aldosteronism (PA) conducted between 2013-2021, with 60 being outpatient procedures; these had a success rate of 95% and no readmissions within 48 hours.
- Results showed low pain levels (average of 2.1/10) and high patient satisfaction (average of 9.4/10) after one day, with over half of patients cured or improved after six months, indicating outpatient LA is both feasible and effective for managing PA.
Article Synopsis
- - The study focused on understanding how common secondary hypertension (2HTN) is in young adults aged 18 to 40, finding that nearly 30% of patients had 2HTN.
- - The most common causes of 2HTN were identified as primary aldosteronism, renovascular hypertension, and kidney diseases, with certain factors like being female and having a lower BMI linked to a higher prevalence.
- - Based on their findings, the researchers recommend that all young adults with hypertension should be screened for secondary causes, as there is a significant risk present regardless of age or blood pressure levels.
Arterial stiffness is an independent predictor of cardiovascular events in different populations. Destiffening appears to be possible through the control of the main cardiovascular risk factors, with however important individual variations. There are so far too few data available on the prognostic importance of changes in arterial stiffness.
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