Galantamine-Memantine Combination in the Treatment of Parkinson's Disease Dementia.

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects over 1% of population over age 60. It is defined by motor and nonmotor symptoms including a spectrum of cognitive impairments known as Parkinson's disease dementia (PDD). Currently, the only US Food and Drug Administration-approved treatment for PDD is rivastigmine, which inhibits acetylcholinesterase and butyrylcholinesterase increasing the level of acetylcholine in the brain.

Use of conjoint analysis to weight biosecurity practices on pasture-based dairy farms to develop a novel audit tool-BioscoreDairy.

Risk assessments are important tools to identify deficits in biosecurity management practices. A major strength of some existing tools is that they facilitate cross-country comparisons. However, a weakness is their failure to account for unique intra-national farming enterprise structures such as, for example, pasture-based dairying.

Hyper-induction of IL-6 after TLR1/2 stimulation in calves with bovine respiratory disease.

Bovine respiratory disease (BRD) is a leading cause of mortality and compromised welfare in bovines. It is a polymicrobial syndrome resulting from a complex interplay of viral and bacterial pathogens with environmental factors. Despite the availability of vaccines, incidence and severity in young calves remains unabated.