Intervention Engagement Moderates the Dose-Response Relationships in a Dietary Intervention.

Behavioral interventions could lead to changes in behavior through changes in a mediator. This dose-response relationship might only hold true for those participants who are actively engaged in interventions. This Internet study investigated the role of engagement in a planning intervention to promote fruit and vegetable consumption in addition to testing the intervention effect on planning and behavior.

Bioactive formulations with sugar-derived surfactants: a new approach for photoprotection and controlled release of promethazine.

Skin deep: A bioactive formulation for dermal delivery of antihistamines is obtained by using the original properties of catanionic associations towards self-assembly in water. The drug, which participates in its own transport, is preserved from photodegradation when solubilised in the bioactive formulation. The drug release through the skin is also delayed.

Intramolecular homolytic substitution of sulfinates and sulfinamides.

A general and efficient method for the synthesis of cyclic sulfinates and sulfinamides based on intramolecular homolytic substitution (S(H)i) at the sulfur atom by aryl or alkyl radicals is described. Both alkyl and benzofused compounds can be accessed directly from easily prepared acyclic precursors. Enantiomerically enriched sulfur-based heterocycles were formed through an S(H)i process with inversion of configuration at the sulfur atom.

Laparoscopic creation of pericardial window.

Malignant pericardial effusions are frequently symptomatic and usually recur after aspiration. Surgical options include pericardiectomy and transthoracic or subxiphoid pericardial window formation and, more recently, thoracoscopic pericardial window formation. The authors report their first four cases of laparoscopic creation of pericardial windows.