Publications by authors named "J D Bremner"
Background: Acute psychological stress may induce physiological changes predisposing individuals to adverse health outcomes through hemodynamic and vascular effects. We studied the association between the aggregated stress-induced changes in hemodynamic and vascular function tests with adverse cardiovascular outcomes in patients with coronary artery disease, after adjusting for sociodemographic and clinical factors.
Methods And Results: Individuals with stable coronary artery disease from 2 prospective cohort studies were studied.
Environmental hazards associated with the global food system threaten societal integrity. Yet, there is a major data gap in the global understanding of how the prevalence of hazards is changing over time, how different classes of hazard are distributed, and whether the combined literature represents hazard prevalence equitably across research, policy and legislation, and news. Here, we explore this data gap, leveraging global research, policy, and news databases.
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- The study investigates how acute psychological stress impacts cardiovascular disease (CVD) mortality, focusing on autonomic dysfunction as indicated by electrocardiographic measures.
- In a cohort of 765 participants with stable CVD, researchers monitored heart rate variability (HRV) during stress tests and found a significant association between decreased HRV during stress and a higher risk of CVD death.
- The findings suggest that both stress-induced decreases in HRV and low resting HRV independently increase the risk of CVD mortality, highlighting the need for further research on managing autonomic dysfunction to improve health outcomes.
Article Synopsis
- PTSD is linked to a higher risk of heart failure hospitalizations in individuals with coronary artery disease, with those diagnosed having a 4.4 times greater risk of hospitalizations compared to those without PTSD.
- The study involved 736 participants, revealing that 9.4% had PTSD, and higher PTSD symptom scores correlated with increased heart failure events.
- While PTSD is strongly associated with heart failure, it does not appear to influence rates of cardiovascular death or nonfatal heart attacks unrelated to heart failure hospitalizations.
Article Synopsis
- COVID infection can lead to Long COVID, which causes various long-term neurological and mental health issues, but the exact causes and range of symptoms are still unclear.
- A literature review from multiple databases highlights that many patients experience symptoms like loss of smell and increased fatigue, alongside significant anxiety and mood disorders.
- Neuropsychological and brain imaging studies indicate a link between the severity of symptoms and cognitive dysfunction, as well as observable changes in brain structure in Long COVID patients, calling for further research to understand the underlying mechanisms.