Publications by authors named "J Craig Fielding"
Exploring the Phenotype and Possible Mechanisms of Palinopsia in Visual Snow Syndrome.
Invest Ophthalmol Vis Sci
October 2024
Purpose: Palinopsia (persistent afterimages and/or trailing) is a common but poorly understood symptom of the neurological condition visual snow syndrome. This study aimed to collect a phenotypical description of palinopsia in visual snow syndrome and probe for abnormalities in temporal visual processing, hypothesizing that palinopsia could arise from increased visibility of normal afterimage signals or prolonged visible persistence.
Methods: Thirty controls and 31 participants with visual snow syndrome (18 with migraine) took part.
Background: Use of electronic health records (EHR) to provide real-world data for research is established, but using EHR to deliver randomised controlled trials (RCTs) more efficiently is less developed. The Allergy AntiBiotics And Microbial resistAnce (ALABAMA) RCT evaluated a penicillin allergy assessment pathway versus usual clinical care in a UK primary care setting. The aim of this paper is to describe how EHRs were used to facilitate efficient delivery of a large-scale randomised trial of a complex intervention embracing efficient participant identification, supporting minimising GP workload, providing accurate post-intervention EHR updates of allergy status, and facilitating participant follow up and outcome data collection.
View Article and Find Full Text PDFPurpose: Visual snow is the hallmark of the neurological condition visual snow syndrome (VSS) but the characteristics of the visual snow percept remain poorly defined. This study aimed to quantify its appearance, interobserver variability, and effect on measured visual performance and self-reported visual quality.
Methods: Twenty-three participants with VSS estimated their visual snow dot size, separation, luminance, and flicker rate by matching to a simulation.
Article Synopsis
- - The study examines the potential impact of improved influenza vaccines on reducing illness and deaths in Australians under 65, estimating the additional morbidity and mortality that could be averted.
- - Researchers analyzed data from 2015-2019, calculating the burden of influenza in a hypothetical unvaccinated population and using this to project benefits from standard versus improved vaccines.
- - Findings suggest that an improved vaccine could prevent between 1,517 to 12,641 influenza cases, 287 to 1,311 hospitalizations, and 9 to 33 deaths annually, mainly when the standard vaccine is less effective.
Article Synopsis
- Reducing antibiotic use in Australia requires various strategies, including better vaccines against bacteria like Streptococcus pyogenes, which commonly causes sore throats, to combat antimicrobial resistance.
- An analysis of general practice data from 2013-2017 revealed that 5.7% of visits were for upper respiratory tract infections (URTIs), with 66.1% of sore throat visits leading to antibiotic prescriptions, often not following guidelines.
- The study suggests that sustained interventions, including effective vaccines for S. pyogenes, are needed to lower unnecessary antibiotic prescribing and align with Australian therapeutic guidelines.