Publications by authors named "J Craig Busey"

Purpose: To evaluate the significance of CT perfusion parameters predicting response to neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma (PDAC).

Materials And Methods: Seventy patients with PDAC prospectively had CT perfusion acquisition incorporated into baseline multiphase staging CT. Twenty-eight who were naïve to therapy were retained for further investigation.

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Article Synopsis
  • The study assessed the feasibility of performing CT perfusion alongside routine multiphase contrast-enhanced CT scans on a 256-slice scanner for patients with pancreatic ductal adenocarcinoma (PDAC).
  • A total of 57 patients underwent CT perfusion acquisition without compromising the quality of standard imaging, providing valuable perfusion metrics for both tumor and healthy pancreas tissue.
  • The results indicated that adding CT perfusion to standard protocols is practical, cost-effective, and time-efficient while producing perfusion data similar to existing dedicated protocols.
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Purpose: To evaluate feasibility of a wide detector liver CT protocol with three acquisitions in the hepatic arterial phase.

Methods: Forty-one patients with cirrhosis prospectively underwent a wide detector axial liver CT protocol. Three 16 cm axial liver acquisitions were obtained during a single breath hold at peak aortic enhancement plus 10, 20, and 25 s.

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Background The accuracy of absolute myocardial blood flow (MBF) from dynamic contrast-enhanced cardiac computed tomography acquisitions has not been fully characterized. We evaluate computed tomography (CT) compared with rubidium-82 positron emission tomography (PET) MBF estimates in a high-risk population. Methods In a prospective trial, patients receiving clinically indicated rubidium-82 PET exams were recruited to receive a dynamic contrast-enhanced cardiac computed tomography exam.

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Objective: The purpose of this study was to compare dual-energy CT (DECT) urography with a 50% reduced iodine dose to single-energy CT (SECT) urography with a standard iodine dose with respect to attenuation of renal vascular and urinary tract structures and with respect to image quality.

Subjects And Methods: The study included 62 patients undergoing evaluation of urinary tract lithiasis, tumor, or hematuria. Thirty-one patients underwent DECT urography with a 50% reduced iodine dose and reconstruction at 50 and 77 keV.

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