Publications by authors named "J Constans"
Article Synopsis
- Holmes tremor (HT) is a disorder that causes different types of tremors and can severely affect a patient's daily life; traditional medications often fail to provide consistent relief.
- This study examines the effectiveness of a new surgical technique, called MRI-guided laser interstitial thermal therapy (MRIgLITT), focusing on its impact on tremor severity, quality of life (QOL), and adverse effects in patients with persistent HT.
- Results showed notable improvements in tremor severity and QOL, with patients experiencing a 41% reduction in tremors at 3 months and a 29% reduction at 12 months post-surgery, indicating the potential benefits of this treatment approach.
Article Synopsis
- Systemic sclerosis (SSc) is a severe disease linked to high mortality rates, primarily due to related health issues known as comorbidities, which were analyzed in this study to create a 'comorbidome.'
- The study involved 400 patients, revealing that specific conditions like cancer, heart disease, and multiple medications significantly contributed to mortality rates.
- The findings emphasized the importance of these comorbidities, although the study's small sample size suggests the need for further research to validate the results and possibly develop a mortality risk assessment tool.
Article Synopsis
- The study aimed to evaluate machine learning and deep learning techniques for detecting systemic scleroderma using nailfold capillaroscopy images from patients in the French SCLEROCAP study.
- Machine learning classifiers showed varying performance, with the best results (F1 score of 0.79) achieved using the light gradient boosting model, while deep learning with DenseNet-121 greatly outperformed with an accuracy of 0.94.
- This research highlights the potential of advanced machine learning and deep learning methods for improving the accuracy of systemic scleroderma diagnosis through image analysis.
Attentional bias and deficits in attentional control are associated with posttraumatic stress disorder (PTSD) symptoms. Attention control training (ACT) may address these factors. We reviewed randomized controlled trials (RCTs) of ACT for PTSD to address unanswered questions about ACT's effectiveness, tolerability, and implementation.
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- The study looked at why people with systemic sclerosis often get painful sores on their fingers (called digital ulcers) and how tiny blood vessel problems contribute to this.
- Researchers measured blood pressure in the fingers of patients to find out if there was a link between lower pressure and the presence of these sores.
- The results showed that a lot of people with ulcers had lower blood pressure in their fingers, suggesting that these blood flow issues play a big role in causing ulcers, separate from other blood vessel problems.