Publications by authors named "J Connor Holman"

Background: Baseline lung allograft dysfunction (BLAD) after lung transplant is associated with an increased risk of dying, but the association with health-related quality of life (HRQL) and exercise capacity is not known. We hypothesized that BLAD would be associated with reduced HRQL and 6-min walk distance (6MWD) at 1 y post-lung transplant.

Methods: We analyzed patients who underwent lung transplants in our program from 2004 to 2018 who completed 1-y 36-item Short Form (SF-36) questionnaire and 6MWD testing.

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Key Points: Peripheral blood biomarkers may have value in monitoring kidney transplant recipients after treatment of acute rejection. The donor-derived cellfree DNA may be more sensitive to identifying antibody-mediated rejection and gene expression profile may be more sensitive to identifying acute cellular rejection.

Background: Persistent rejection is an increasingly recognized barrier to long-term kidney allograft survival.

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Article Synopsis
  • The 2022 guidelines for fall prevention recommend assessing sensory functions like dizziness, vision, and hearing, but these factors aren't incorporated in current falls risk evaluation tools.
  • A study analyzed data from elderly patients assessed in an emergency department to explore how these sensory impairments might affect falls risk.
  • Findings indicated that most patients fell into high or low-risk categories, highlighting the need to adjust criteria for intermediate risk, particularly since hearing loss and dizziness were linked more strongly to fall incidents than vision or balance.
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Introduction: The successes in the field of pediatric kidney transplantation over the past 60 years have been extraordinary. Year over year, there have been significant improvements in short-term graft survival. However, improvements in longer-term outcomes have been much less apparent.

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Background: Persistent rejection is an increasingly recognized barrier to long-term kidney allograft survival. A noninvasive method to help identify patients with persistent rejection in need of biopsy would be valuable.

Methods: This was a post-hoc analysis of a multicenter observational study.

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