Publications by authors named "J Conejo-Mir-Sanchez"
Article Synopsis
- - Biological therapy, specifically brodalumab, shows promise in treating hidradenitis suppurativa (HS) by targeting the IL-17 receptor, which may play a role in the disorder's immune dysregulation.
- - A study involving 16 adults with moderate to severe HS found that 50% achieved an improvement in symptoms and experienced a significant decrease in disease severity after 16 weeks of brodalumab treatment.
- - The treatment was generally safe, with some patients experiencing mild adverse effects, suggesting that brodalumab is a viable option for those who did not respond to previous biologics like adalimumab.
Article Synopsis
- Lipoid proteinosis (LP) is a rare genetic skin disorder caused by ECM1 gene mutations, leading to abnormal material accumulation in skin and organs.
- The case report focuses on a 48-year-old man with LP who improved significantly after treatment with oral acitretin, while a systematic review was conducted to gather and evaluate related studies on LP management.
- The review included 25 studies and analyzed data from 44 patients, suggesting that low-dose acitretin may be a promising treatment option with fewer side effects, but highlights the need for further research to develop better treatment guidelines.
Article Synopsis
- - Oculocutaneous albinism (OCA) is a genetic disorder affecting melanin production, studied in pediatric patients through dermatological and ophthalmological exams, including advanced imaging techniques like OCT.
- - The study found that individuals with a single pathogenic mutation showed milder symptoms, while more severe cases were linked to a greater number of genetic mutations and polymorphisms.
- - A common observation across all OCA subgroups was paler dermoscopic patterns, particularly varied vascular patterns, which indicated more severe presentations of the disease.
Thermography for the follow-up of skin and soft tissue infections.
Enferm Infecc Microbiol Clin (Engl Ed)
June 2023
Background: Ultraviolet radiation is the main environmental risk factor responsible for the development of skin cancer. Other occupational, socioeconomic, and environmental factors appear to be related to the risk of skin cancer. Furthermore, the factors appear to differ for melanoma and non-melanoma skin cancer (NMSC).
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