Publications by authors named "J Christopher Culberson"
Article Synopsis
- Dementia is a widespread issue in the U.S., affecting millions and highlighting the need for healthy cognitive aging to enhance well-being and quality of life.
- A research study in West Texas explored how lifestyle factors like sleep, diet, and exercise relate to brain atrophy in older adults with mild cognitive impairment (MCI), Alzheimer's disease (AD), and healthy individuals.
- Findings indicate that sleep deprivation and low physical activity are linked to brain volume loss, while diet—particularly fruit and vegetable intake—affects certain brain regions, stressing the necessity for lifestyle changes to support cognitive health and prevent disease.
Objective: To determine associations between Vitamin D (VD) levels and clinical depression through the Geriatric Depression Scale (GDS) and its questions and subdomains, stratified by demographics and Hispanic/Latino ethnicity (HLE).
Design, Setting, And Participants: A cohort of 299 Project FRONTIER participants aged 62.6 ± 11.
Healthy aging is the process of preserving and enhancing one's independence, physical and mental well-being, and overall quality of life. It involves the mental, emotional, and cognitive wellness. Although biological and genetic factors have a significant influence on the process of aging gracefully, other adjustable factors also play a crucial role.
View Article and Find Full Text PDFThe ageing process begins at birth. It is a life-long process, and its exact origins are still unknown. Several hypotheses attempt to describe the normal ageing process, including hormonal imbalance, formation of reactive oxygen species, DNA methylation & DNA damage accumulation, loss of proteostasis, epigenetic alterations, mitochondrial dysfunction, senescence, inflammation, and stem cell depletion.
View Article and Find Full Text PDFAlzheimer's disease (AD) and Alzheimer's disease-related disorders (ADRD) are late-onset, age-related progressive neurodegenerative disorders, characterized by memory loss and multiple cognitive impairments. Current research indicates that Hispanic Americans are at an increased risk for AD/ADRD and other chronic conditions such as diabetes, obesity, hypertension, and kidney disease, and given their rapid growth in numbers, this may contribute to a greater incidence of these disorders. This is particularly true for the state of Texas, where Hispanics are the largest group of ethnic minorities.
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