Evolving Guidelines for the Use of Touch During a Clinical Trial of Group Psilocybin-Assisted Therapy.

For a new clinical trial testing a group retreat-based format of psilocybin-assisted therapy, our research team created an initial set of practice guidelines that aimed to describe facilitator use of touch in a way that is ethical, supportive, and minimizes harm. In our first three retreats, however, we had two unexpected experiences with touch that led us to iterate our initial guidelines into a new version of guidelines. In this Technical Report, we describe our evolving guidelines specifying acceptable practices for facilitator use of touch to ensure a safe, supportive, and therapeutic participant experience.

The Mentorship Blueprint: A Comprehensive Review for the Development of Programs in Pharmacy Education.

Mentorship has benefits for students and faculty, helping to support their professional development, connectedness, and career endeavors. While the value of mentorship programs is well documented in the literature, there is less practical guidance and few compiled resources to start a program. This paper reviews different mentorship practices in pharmacy education and provides a list of strategies to develop high-functioning mentorship programs or groups.

Controlled human infection model of Neisseria lactamica in late pregnancy investigating mother-to-infant transmission in the UK: a single-arm pilot trial.

Background: The infant respiratory microbiome is derived largely from the mother and is associated with downstream health and disease. Manipulating maternal respiratory flora peripartum to influence the infant microbiome has not previously been investigated. Neisseria lactamica is a harmless pharyngeal commensal that correlates inversely with Neisseria meningitidis carriage and disease.

Patellofemoral positioning CT protocol has diagnostic ability to differentiate patellar maltracking phenotype.

Introduction: Traditional radiographs often fail to capture the dynamic nature of patellar maltracking in patellofemoral pain syndrome (PFPS) and patellar instability, necessitating improved diagnostic protocols. This study aimed to: (1) introduce a CT protocol with scans at three knee positions (45° flexion, extension, and extension with quadriceps contraction), (2) assess how positioning influences patellofemoral indices measured from radiographs and CT, and (3) to evaluate the protocol's ability to classify maltracking phenotypes: dislocator, subluxator, or symptomatic without dislocation/subluxation (Neither).

Methods: Patients who underwent surgery for PFPS from April to December 2022 were retrospectively reviewed.

Characteristics of TSPO expression in marmoset EAE.

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) and is a leading non-traumatic cause of disability in young adults. The 18 kDa Translocator Protein (TSPO) is a mitochondrial protein and positron emission tomography (PET)-imaging target that is highly expressed in MS brain lesions. It is used as an inflammatory biomarker and has been proposed as a therapeutic target.