Functional food science and defence against reactive oxidative species.

This paper assesses critically the science base that underpins the argument that oxidative damage is a significant causative factor in the development of human diseases and that antioxidants are capable of preventing or ameliorating these disease processes. The assessment has been carried out under a number of headings, and some recommendations for future research are made based on the present day knowledge base. The knowledge database (1) Consideration of the basic science that underlies understanding of the role of free radicals in causing cellular pathologies, and the role of antioxidants in preventing this, shows that an imbalance of reactive oxygen species and antioxidant defence systems may lead to chemical modifications of biologically relevant macromolecules.

[Viscous human collagen IV. Physical properties and experimental tolerance].

Viscous solutions of collagen IV have been used experimentally on rabbits and monkeys. The physical properties of the solution allow a first class visco-surgery. Tolerance is studied: degradation and absorption in the anterior chamber, intraocular pressure, endothelial effects, biological sensitivity.