Publications by authors named "J Champsi"
Article Synopsis
- - The study evaluated the prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) among Kaiser Permanente Northern California patients in the wake of the COVID-19 pandemic, involving nearly 10,000 adults.
- - An estimated 1.67% of participants reported ME/CFS-like illness, with about 14.12% of those cases occurring after a COVID-19 infection, particularly among unvaccinated individuals or those who had COVID-19 early in the pandemic.
- - Despite the findings, the overall impact of COVID-19 on increasing rates of ME/CFS-like illness appeared minimal during the study period, but those identified with the illness experienced significant impairments in multiple areas of functioning
Article Synopsis
- The study analyzed treatment options for uncomplicated streptococcal bloodstream infections (BSI) in adults, focusing on antibiotic duration (5-10 days vs. 11-15 days) and route (oral switch vs. intravenous).
- The results indicated that shorter 5-10 day antibiotic courses were not worse than longer durations, suggesting they could be an effective treatment alternative.
- However, oral switch therapy did not prove to be non-inferior compared to complete intravenous treatment, highlighting the need for further randomized controlled trials to confirm these findings and optimize treatment guidelines.
Introduction: Centers of excellence and bundled payment models have driven perioperative optimization and surgical site infection (SSI) prevention with decolonization protocols and antibiotic prophylaxis strategies. We sought to evaluate time trends in the incidence of deep SSI and its causative organisms after six orthopaedic procedures in a US-based integrated healthcare system.
Methods: We conducted a population-level time-trend study using data from Kaiser Permanente's orthopaedic registries.
Article Synopsis
- Chronic hepatitis C virus (HCV) infection significantly increases the risk of developing various types of cancers, particularly liver cancer, compared to those without HCV.
- A study examining data from 2007 to 2017 found that individuals with HCV were more susceptible to several cancers, including hematologic, lung, pancreatic, oral, and anal cancers.
- Treatment with direct-acting antivirals (DAA) appears to lower the risk of liver and hematologic cancers in patients with HCV.
Among 25 291 and 4 921 830 people with and without hepatitis C, life expectancy at age 20 increased 1.8 years and 0.3 years from the interferon to interferon-free era, respectively.
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