Publications by authors named "J Chaffin"

This case is a rare presentation of severe aplastic anemia in a 31-year-old male with acquired clonality of the X chromosome as the sole cytogenetic abnormality. This abnormality has not been reported to our knowledge, and the significance of this finding remains unclear. Comprehensive diagnostic workup included bone marrow biopsy, cytogenetic analysis, and Next-Generation sequencing, which revealed no tier I/II variants typically associated with clonal hematopoietic disorders.

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Cyanobacterial blooms in the western basin of Lake Erie have been well studied with a focus on planktonic and the cyanotoxin microcystin, but recent research has shown that blooms are not entirely . Previous studies have documented other taxa in blooms capable of producing other cyanotoxins. Furthermore, benthic cyanobacteria have historically been overlooked in Lake Erie.

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Cyanobacterial harmful algae blooms (cyanoHABs) are a global threat to water resources, and lake managers need effective strategies to suppress or control them. Algaecides may have negative environmental impacts, and their use is becoming restricted. Nanobubble ozone technology (NBOT) is an emerging water treatment option with potentially fewer negative impacts.

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Although evidence indicates that viruses are important in the ecology of spp., many questions remain. For example, how does exist at high, bloom-associated cell concentrations in the presence of viruses that infect it? The phenomenon of lysogeny and associated homoimmunity offer possible explanations to this question.

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A 72-year-old man who underwent bilateral orthotropic lung transplantation for interstitial lung disease 6 months ago presented to the clinic with a 2-week history of cough, shortness of breath, and mid-back pain. The donor was negative for cytomegalovirus (CMV) and positive for Epstein-Barr virus (EBV), and the recipient was positive for both CMV and EBV. He also reported headaches but denied any fever, chills, weight loss, night sweats, chest pain, orthopnea, paroxysmal nocturnal dyspnea, or leg swelling.

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