Publications by authors named "J Cejkova"
Article Synopsis
- In the mid-20th century, molecular biology and information-communication theory emerged, initially leading to a deep synergy in understanding genetic codes and their meanings.
- Over time, despite advancements, the collaboration between these fields has faced challenges that complicate efforts in next-generation biology, including personalized therapies and protein production.
- To overcome these challenges, a paradigm shift in theoretical biology is necessary, demanding a multidisciplinary approach that incorporates insights from various fields, including Artificial Life.
Background: Ionizing radiation DNA damage is the main mechanism of radiotherapy (RT) action and the outcome of treatment and healthy tissue toxicity is influenced by a number of external and internal factors, including mutations in DNA damage recognition and repair. Disorders of DNA repair may result in increased sensitivity to cancer treatment.
Purpose: The mechanism of DNA repair and an overview of genetic syndromes with mutations in genes involved in DNA repair clarify the accelerated carcinogenesis and increased radiosensitivity in RT cancers.
Vibrational spectroscopic analysis of critical micelle concentration in sodium decanoate solutions.
Spectrochim Acta A Mol Biomol Spectrosc
April 2021
The presented study is devoted to the investigation of the micellization-induced liquid-liquid fluctuations in sodium decanoate (NaD) aqueous solutions, based on the vibrational spectroscopic study of NaD and the determination of critical micelle concentration (CMC) of this system. At the same time, we focused on monitoring the effect of the addition of decanol to this system and changing its basic parameters from the point of view of CMC. CMC is an important parameter from a practical point of view and a characteristic feature of each micelle-forming compound.
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