Publications by authors named "J Cason"

Article Synopsis
  • This protocol outlines a Cochrane Review focused on the timing of vitrectomy following open-globe injuries.
  • The main goal is to compare the effects of performing the surgery early versus later on patients' visual outcomes.
  • The review aims to provide evidence that could guide clinical decisions regarding the optimal timing for vitrectomy in such cases.
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The identification of informative molecular markers is useful for linkage mapping and can benefit genome-wide association studies by providing fine-scale information about sequence variations. However, high-throughput genotyping approaches are not cost-effective for labs that require frequent use, such as breeding programs that need to perform genotyping on large populations with hundreds of individuals. The number of single nucleotide polymorphism markers generated by those approaches can be far more than needed for most breeding programs; instead, breeders focus on the use of at most hundreds of polymorphic molecular markers for analysis.

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Purpose: When severe retinal and corneal injury occur together, a temporary keratoprosthesis (TKP) is often a last resort to allow posterior segment visualization to enable vitreoretinal surgery, followed by a penetrating keratoplasty (PKP) which can restore corneal clarity in a single operation. We aimed to assess visual outcomes following combined PKP and vitreoretinal surgery with the use of a TKP for cases of ocular trauma.

Design: A systematic literature review was performed following PRISMA guidelines (PROSPERO registration number: CRD42023423518).

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Article Synopsis
  • * Timely surgical intervention is crucial to reduce the risk of serious complications like endophthalmitis, which can affect visual outcomes.
  • * A review of 15 studies showed that repairs done within 24 hours significantly lowered the odds of endophthalmitis, but visual outcomes were similar regardless of repair timing.
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