Diabetes Mellitus Is Not a Risk Factor for Difficult Intubation Among Critically Ill Adults: A Secondary Analysis of Multicenter Trials.

Objectives: Diabetes mellitus has been associated with greater difficulty of tracheal intubation in the operating room. This relationship has not been examined for tracheal intubation of critically ill adults. We examined whether diabetes mellitus was independently associated with the time from induction of anesthesia to intubation of the trachea among critically ill adults.

State-level changes in racial disparities in probation and parole rates in the United States, 2001-2018.

Although the public health field has increasingly studied the collateral consequences of incarceration, we know little about the health consequences of other forms of criminal legal contact, including probation and parole. Understanding spatial and racial-ethnic variation in probation/parole across US states provides new insights into how community supervision impacts population health disparities. However, state-level probation/parole prevalence has not been adequately described.

Variation in the Impact of New York on Pause on Traffic Congestion by Racialized Economic Segregation and Environmental Burden.

During the 2019 coronavirus pandemic, stay-at-home policies such as New York's (NY) NY on Pause dramatically reduced traffic congestion. Despite high traffic burden in NY's environmental justice communities, this reduction has not been evaluated through an environmental justice lens-our objective in this analysis. We obtained census tract-level traffic congestion data from Google traffic maps hourly for 2018-2020.

Fostamatinib for Hospitalized Adults With COVID-19 and Hypoxemia: A Randomized Clinical Trial.

Importance: Fostamatinib, a spleen tyrosine kinase inhibitor, has been reported to improve outcomes of COVID-19.

Objective: To evaluate the efficacy and safety of fostamatinib in adults hospitalized with COVID-19 and hypoxemia.

Design, Setting, And Participants: This multicenter, phase 3, placebo-controlled, double-blinded randomized clinical trial was conducted at 41 US sites and 21 international sites between November 17, 2021, and September 27, 2023; the last follow-up visit was December 31, 2023.

Benefit of early oseltamivir therapy for adults hospitalized with influenza A: an observational study.

Background: clinical guidelines recommend initiation of antiviral therapy as soon as possible for patients hospitalized with confirmed or suspected influenza.

Methods: A multicenter US observational sentinel surveillance network prospectively enrolled adults (aged ≥18 years) hospitalized with laboratory-confirmed influenza at 24 hospitals during October 1, 2022-July 21, 2023. A multivariable proportional odds model was used to compare peak pulmonary disease severity (no oxygen support, standard supplemental oxygen, high-flow oxygen/non-invasive ventilation, invasive mechanical ventilation, or death) after the day of hospital admission among patients starting oseltamivir treatment on the day of admission (early) versus those who did not (late or not treated), adjusting for baseline (admission day) severity, age, sex, site, and vaccination status.