Publications by authors named "J Carlos Alvarado"

Latin Americans have a rich genetic make-up that translates into heterogeneous fractions of the autosomal genome in runs of homozygosity (F) and heterogeneous types and proportions of indigenous American ancestry. While autozygosity has been linked to several human diseases, very little is known about the relationship between inbreeding, genetic ancestry, and cancer risk in Latin Americans. Chile has one of the highest incidences of gallbladder cancer (GBC) in the world, and we investigated the association between inbreeding, GBC, gallstone disease (GSD), and body mass index (BMI) in 4029 genetically admixed Chileans.

View Article and Find Full Text PDF

Background: Adolescents and young are one of the population groups with the highest prevalence of anxiety and depression worldwide. Few studies address this problem in young university students. This study aimed to analyze the prevalence of anxiety and depression in first-year university students and its association with family functionality and social support.

View Article and Find Full Text PDF
Article Synopsis
  • Measuring deeply virtual Compton scattering (DVCS) on the neutron is essential for understanding the nucleon's structure through generalized parton distributions (GPDs).
  • Neutron targets help complement data obtained from polarized protons, particularly in determining the poorly understood GPD E, which is crucial for analyzing quark contributions to nucleon spin.
  • The experiment utilized a longitudinally polarized electron beam at Jefferson Lab and the CLAS12 detector to measure DVCS on the neutron for the first time, providing new insights into quark-flavor separation of relevant Compton form factors.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to find early indicators of presbycusis (age-related hearing loss) by analyzing auditory brainstem response (ABR) waves in Wistar rats of different ages.
  • Researchers observed that wave II amplitudes decreased significantly in 9-month-old rats, even though hearing thresholds didn't show noticeable decline until 14 months.
  • These results suggest that changes in ABR waves might indicate early signs of hearing loss before any significant changes in hearing ability, which could help in early diagnosis and treatment in humans to improve quality of life for those affected.
View Article and Find Full Text PDF