Safety and Efficacy of Adding Fixed-Combination Brinzolamide/Timolol Maleate to Prostaglandin Therapy for Treatment of Ocular Hypertension or Glaucoma.

Purpose. To evaluate the safety and efficacy of adding brinzolamide 1%/timolol maleate 0.5% fixed combination (BTFC) to a prostaglandin analog (PGA).

Traumatic optic neuropathy: to treat or not to treat? Report of two cases.

Case Reports: We present two cases of blunt ocular trauma with clinical findings and complementary tests compatible with traumatic optic neuropathy (TON), and progression to sectorial optic atrophy.

Discussion: TON have an essentially clinical diagnosis, and in the last few years has been treated with high doses of intravenous steroids, based on weak evidence of the benefit of the steroids in cases of medular trauma. Nevertheless, subsequent studies have concluded that there is a relatively high proportion of cases in all series with spontaneous visual recovery, and there was no convincing evidence of a benefit of steroids compared to observation only.

Reliability of noncontact pachymetry after laser in situ keratomileusis.

Purpose: To assess the repeatability and reproducibility of central corneal thickness (CCT) measurements obtained by combined scanning-slit/Placido-disc topography (Orbscan II; Bausch & Lomb, Rochester, NY) after laser in situ keratomileusis (LASIK) and to compare the results with another noncontact method, specular microscopy (SP-2000P; Topcon, Tokyo, Japan).

Methods: To analyze intrasession repeatability, one examiner measured 22 postmyopic LASIK eyes 10 times successively in the shortest time possible, using both devices randomly. To study intersession reproducibility, the same operator obtained measurements from another 50 eyes with stable refraction in two consecutive visits at the same time of the day between 6 and 9 months after myopic LASIK.

Antibacterial and antifungal effects of soft contact lens disinfection solutions.

Aims: To study the antibacterial and antifungal effects of soft contact lens disinfection solutions.

Methods: Eight contact lens disinfection solutions containing hydrogen peroxide or biguanides or polyquad compounds were evaluated with respect to their ability to disinfect a saline solution experimentally contaminated with different bacteria and with a fungus. We used cultures in blood Agar, MuellerHinton agar and Saboureaud's agar to identify the bacterial and fungal growth following 14 h of exposure to the disinfection solutions.