Publications by authors named "J Canive"
Article Synopsis
- - The study explores the differences in cognitive impairment between schizophrenia (SZ) and bipolar disorder (BD), hypothesizing a link between genetic risk factors, brain connectivity, and cognitive performance in SZ patients compared to BD patients.
- - Researchers used genome-wide data to identify genetic markers associated specifically with SZ and examined their impact on brain connectivity and cognitive functions, finding that SZ patients had greater reductions in brain connectivity and more severe cognitive deficits than BD patients.
- - The findings highlight a potential pathway where SZ-related genetic factors lead to disrupted brain connectivity, which may be essential for developing targeted treatments and improving patient outcomes based on their specific cognitive needs.
Objective: We propose and develop a novel biclustering (N-BiC) approach for performing N-way biclustering of neuroimaging data. Our approach is applicable to an arbitrary number of features from both imaging and behavioral data (e.g.
View Article and Find Full Text PDFBackground: Auditory encoding abnormalities, gray-matter loss, and cognitive deficits are all candidate schizophrenia (SZ) endophenotypes. This study evaluated associations between and heritability of auditory network attributes (function and structure) and attention in healthy controls (HC), SZ patients, and unaffected relatives (UR).
Methods: Whole-brain maps of M100 auditory activity from magnetoencephalography recordings, cortical thickness (CT), and a measure of attention were obtained from 70 HC, 69 SZ patients, and 35 UR.
Characterizing the Effects of Quetiapine in Military Post-Traumatic Stress Disorder.
Psychopharmacol Bull
February 2018
Objectives: A previous randomized placebo-controlled trial in military veterans posttraumatic stress disorder (PTSD) found that quetiapine improved global PTSD symptoms severity, depression and anxiety as well as the re-experiencing and hypearousal clusters. However, it is not known if individual symptoms had a preferential response to this medication. The goal of this study was to analyze the individual symptom response in this group of patients.
View Article and Find Full Text PDFMagnetoencephalography (MEG) and EEG have identified poststimulus low frequency and 40 Hz steady-state auditory encoding abnormalities in schizophrenia (SZ). Negative findings have also appeared. To identify factors contributing to these inconsistencies, healthy control (HC) and SZ group differences were examined in MEG and EEG source space and EEG sensor space, with better group differentiation hypothesized for source than sensor measures given greater predictive utility for source measures.
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