Publications by authors named "J Camilla Stark"
High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.
View Article and Find Full Text PDFArticle Synopsis
- Repeat-mediated deletions (RMDs) occur when repetitive DNA elements bridge breaks in DNA, leading to the loss of certain sequences; this process requires careful resolution of sequence differences between the repeats.
- The MLH1 protein and its partner PMS2 are essential for both preventing RMDs and resolving sequence divergence in these deletions.
- Mutant studies of MLH1 and PMS2 reveal distinct functions where some mutants show defects in both suppression and resolution, while others affect only one function, suggesting a complex relationship between these processes.
Introduction: Lyme disease (LD) is caused by infection with the bacteria Borrelia burgdorferi sensu lato (Bb) through the bite of an infected Ixodes spp. tick. LD has emerged as a public and animal health issue in Canada, with human incidence increasing in part due to the expansion of Ixodes scapularis ticks and their vertebrate hosts.
View Article and Find Full Text PDFMammalian RAD52 is a DNA repair factor with strand annealing and recombination mediator activities that appear important in both interphase and mitotic cells. Nonetheless, RAD52 is dispensable for cell viability. To query RAD52 synthetic lethal relationships, we performed genome-wide CRISPR knock-out screens and identified hundreds of candidate synthetic lethal interactions.
View Article and Find Full Text PDFArticle Synopsis
- The study explores how active travel impacts children's heart rates, demonstrating that modes of active travel are linked to increased physiological responses.
- The research involved 73 children from three schools in Austria, utilizing a mixed survey design over a 7-day observation period.
- Results indicate that feelings of exhaustion and stress raise heart rates, while social factors, such as traveling alone or with peers, also affect physiological responses.