Publications by authors named "J Cadamuro"

This is the first in a series of five papers that detail the role and substantial impact that external quality assessment (EQA) and their providers' services play in ensuring diagnostic (IVD) performance quality. The aim is to give readers and users of EQA services an insight into the processes in EQA, explain to them what happens before EQA samples are delivered and after examination results are submitted to the provider, how they are assessed, what benefits participants can expect, but also who are stakeholders other than participants and what significance do EQA data and assessment results have for them. This first paper presents the history of EQA, insights into legal, financing and ethical matters, information technology used in EQA, structure and lifecycle of EQA programs, frequency and intensity of challenges, and unique requirements of extra-examination and educational EQA programs.

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Reported tick-borne-encephalitis (TBE) cases have been increasing in Western Austria, but no data are available on vaccination- and infection-specific seroprevalence. This study aimed to estimate current TBEV-seroprevalence in the region and inform prevention programs by comparing anti-NS1-based-incidence rates with reported case numbers and vaccination coverage. Between December 2023 and February 2024, serum samples from 4619 blood donors in Western Austria were collected and analyzed using TBEV- and WNV-IgG-ELISA assays.

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Background: As the healthcare sector evolves, Artificial Intelligence's (AI's) potential to enhance laboratory medicine is increasingly recognized. However, the adoption rates and attitudes towards AI across European laboratories have not been comprehensively analyzed. This study aims to fill this gap by surveying European laboratory professionals to assess their current use of AI, the digital infrastructure available, and their attitudes towards future implementations.

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Article Synopsis
  • Older adults still face high risks of severe outcomes from COVID-19, even with the milder Omicron variant, due to weakened immune responses and insufficient data on antibody efficacy.
  • A study involving 785 older patients found that those with low antibody levels (< 1,200 BAU/mL) had significantly higher mortality and critical care needs compared to those with higher levels.
  • The findings suggest that monitoring antibody levels might be more effective than relying solely on vaccination status to protect older adults from severe COVID-19 outcomes.
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Article Synopsis
  • Clinical labs have gotten way better at using tech to manage and share medical data, thanks to advanced systems and software.
  • Although Laboratory Information Systems (LIS) have improved since the 1970s, they still struggle to handle all the extra information produced during testing.
  • The paper suggests splitting this information into two types—metadata (which describes data) and peridata (which helps understand test results)—to make it easier to use and improve healthcare technology.
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