Publications by authors named "J Cacicedo"
To estimate the cost-effectiveness of cetuximab in combination with radiotherapy compared with radiotherapy alone, for the treatment of locally advanced head and neck cancer patients in Spain. A probabilistic Markov model (second-order Monte Carlo simulation) with a five-year time horizon and quarterly Markov cycles was performed from the perspective of the Spanish National Health System (NHS). The additional cost and quality-adjusted life-year (QALY) gain per patient receiving radiotherapy in combination with cetuximab compared with radiotherapy alone was €4356 (95% CI: €4350-4362) and 0.
View Article and Find Full Text PDFBackground/aim: Many patients with non-small cell lung cancer (NSCLC) receive palliative radiotherapy (RT). Several factors were analyzed to aid in prescribing an optimal treatment for these patients.
Patients And Methods: This prospective observational multicenter study investigated several potential factors for associations with overall survival (OS) in 61 patients with NSCLC receiving palliative RT with or without chemotherapy (CT).
Article Synopsis
- Patients with head and neck cancer (HNC) often experience significant mental health challenges, particularly depressive and anxiety symptoms, especially during and after radiotherapy (RT).
- A systematic review of 18 studies with nearly 2,000 participants revealed a peak in depressive symptoms shortly after RT, with rates decreasing over time, while anxiety symptoms showed a continuous decline.
- Demographics indicated that female and married patients had higher levels of depression, while those who had surgery reported fewer anxiety symptoms; highlighting the need for mental health support during the RT process.
Radiotherapy with 15 × 2.633 Gy vs. 20 × 2.0 Gy in Patients with Malignant Spinal Cord Compression and Favorable Survival Prognoses: A Secondary Analysis of the RAMSES-01 Trial.
Cancers (Basel)
October 2024
Many patients with malignant spinal cord compression (MSCC) who are not candidates for neurosurgery receive radiotherapy alone. This study compared 15 × 2.633 Gy over three weeks to 20 × 2.
View Article and Find Full Text PDFArticle Synopsis
- - This study explored the impact of AI-assisted contouring on radiation oncologists' (ROs) efficiency and accuracy in low- and middle-income countries (LMICs), addressing a gap in previously concentrated research from high-income nations.
- - Ninety-seven ROs were divided into groups using either manual or AI-assisted methods for contouring organs-at-risk (OARs) in two head-and-neck cancer cases, with teaching sessions evaluating their effects on contour quality and time.
- - Findings showed that AI-assisted contouring improved contour quality for several OARs and significantly reduced contouring time, suggesting that it is a safe and effective method, although further clinical trials are needed to fully validate these results.