Publications by authors named "J C van Huijstee"
Article Synopsis
- Adalimumab alone for treating hidradenitis suppurativa (HS) has a maximum effectiveness of only 60%, and its impact on draining tunnels is limited, which leads to the exploration of improving therapy with antibiotics.
- A study compared the effects of adalimumab combined with antibiotics (clindamycin and rifampicin) against adalimumab alone over 12 weeks, with results showing that the combination therapy significantly outperformed the monotherapy.
- The combination therapy resulted in greater improvements in the severity of HS, including a more significant reduction in symptoms and pain, specifically showing better outcomes in reducing draining tunnels associated with the condition.
Article Synopsis
- The study investigates the effectiveness of combining adalimumab, a biologic treatment, with surgery versus using adalimumab alone in patients with moderate to severe hidradenitis suppurativa.
- Results show that the combination treatment led to significantly better reductions in both the severity of the disease and improvements in quality of life after 12 months compared to monotherapy.
- The study has limitations, including a short follow-up period that prevents assessment of long-term surgical recurrence rates.
Needle-free jet injectors are used for the intralesional treatment of various dermatological indications. However, a systematic review that evaluates the efficacy and safety of these treatments has not been published. The objectives of this study are to evaluate the efficacy and safety of needle-free jet injections for dermatological indications and to provide evidence-based treatment recommendations.
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