Imaging in sarcoid disease.

Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating granulomas and variable clinical manifestations, most commonly affecting the lungs, skin, heart, and nervous system. Imaging is central in its diagnosis, staging, and management, providing essential insights into organ involvement and disease activity. Pulmonary manifestations remain the hallmark, with modalities such as high-resolution chest computed tomography (CT) and chest radiography offering critical diagnostic clues.

Consideration of evidence-based training content to strengthen coach recognition of concussion during youth sports activities.

Objective: To synthesize requirements and recommendations addressing sport-related concussion (SRC).

Design: Qualitative study.

Setting: Scholastic and non-scholastic athletic programs.

Dynamically Generated Carbenium Species via Photoisomerization of Cyclic Alkenes: Mild Friedel-Crafts Alkylation.

The torsional strain of -configured medium-sized (6-8) cycloalkenes imparts substantial potential energy efficiently toward ionic additions through generated reactive carbenium species. These reactions have been underexplored due to a historical necessity for harsh ultraviolet irradiation. We report here the Friedel-Crafts (FC) type reactivity of arylcycloalkenes (ACs) and π-nucleophiles for the first time with weak Brønsted acid and visible light energy transfer catalysis.

Musculoskeletal manifestations of systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease affecting nearly every organ system in the body. The musculoskeletal (MSK) system is frequently affected and often the earliest site of disease presentation. Tendon, tendon sheath, bone, muscle, and soft tissue involvement is assessed through a multimodality approach.

Whole liver phase-based R2 mapping in liver iron overload within a breath-hold.

Purpose: Diagnosis and treatment monitoring of iron overload increasingly relies on non-invasive MRI-based measurement of liver iron concentration (LIC). Liver R mapping is known to correlate well with LIC. However, traditional spin-echo based R mapping methods have drawbacks such as long acquisition times and limited volumetric coverage.