Publications by authors named "J C Toto"

Article Synopsis
  • Cameroon has experienced significant urban population growth, with over 67% of urban residents living in slums, and these areas are expanding at a rate of 5.5% annually, prompting concerns about disease transmission and mosquito populations.
  • A review of 85 studies from 2002-2021 identified 10 diseases transmitted by mosquitoes, with rising prevalence rates in urban areas for diseases like dengue, while rural areas saw the emergence of previously absent diseases such as Lymphatic filariasis and Rift valley fever.
  • Malaria prevalence remained stable in urban settings but decreased in rural areas during the same period, highlighting different disease dynamics in urban versus rural environments.
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Article Synopsis
  • Malaria is a significant health issue in Cameroon, prompting a study of malaria vector surveillance conducted from October 2018 to September 2020 across five sites in the country.
  • Various methods were employed, including human landing catches and light traps, to measure aspects like mosquito density and infection rates, ultimately collecting over 139,000 Anopheles mosquitoes from multiple species.
  • Anopheles gambiae was identified as the primary malaria vector, with a high indoor biting rate observed and significant variations in infection rates and human biting rates across different locations.
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Article Synopsis
  • Understanding the mechanisms behind insecticide resistance in malaria vectors is crucial for effective vector control, specifically focusing on metabolic resistance and genetic variations in North Cameroon.
  • The study compared mosquito populations from different regions before and after the distribution of long-lasting insecticidal nets (LLINs), finding increased metabolic resistance in one area, while two others showed decreased effectiveness.
  • Genetic analysis showed mixed trends in resistance alleles, indicating evolving resistance patterns, and emphasized the need for alternative vector control methods alongside LLINs in North Cameroon.
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Previous studies have indicated widespread insecticide resistance in malaria vector populations from Cameroon. However, the intensity of this resistance and underlying mechanisms are poorly known. Therefore, we conducted three cross-sectional resistance surveys between April 2018 and October 2019, using the revised World Health Organization protocol, which includes resistance incidences and intensity assessments.

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