Publications by authors named "J C Sanchez-Gutierrez"
Effect of umbilical cord length on early fetal biomechanics.
Comput Methods Biomech Biomed Engin
January 2021
Article Synopsis
- - The umbilical cord is crucial for fetal development, influencing fetal movements and mechanical loads that support growth, but its dynamics during early development are not well understood.
- - A 2D computational model was created to analyze how different umbilical cord lengths (ranging from 0.060 m to 0.014 m) affect fetal movement, revealing the shortest cord length results in significantly higher linear velocity and increased tension on the fetus.
- - Findings suggest that even small differences in cord length (like the 0.003 m variation between the shortest and the second shortest) can lead to considerable biomechanical changes, offering new insights for clinicians about potential correlations between cord length and fetal pathologies.
Background: Evidence suggests that medial pterygoid muscle plays an important role in temporomandibular pain. Therapeutic approaches targeting this muscle are needed.
Objective: To determine if a solid needle accurately penetrates the medial pterygoid muscle during the application of dry needling.
Cav. (Apocynaceae) is a shrubby plant endemic of Mexico which has been used in traditional medicine. However, the bioactive potential of this plant remains unexplored.
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- Despite numerous clinical trials, there is currently no effective pharmacological treatment for Fragile-X syndrome (FXS), prompting the exploration of epigallocatechin-3-gallate (EGCG) as a potential therapy.
- Preclinical studies in Fmr1 knockout mice indicated that EGCG can enhance memory, and a phase I clinical trial showed that FXS patients treated with EGCG plus cognitive training experienced significant cognitive improvements compared to those on a placebo.
- The findings suggest that further phase 2 clinical trials with larger participant groups are needed to confirm EGCG's effectiveness in improving cognition and daily functioning for individuals with FXS.
Fe-based oxide dispersion strengthened (ODS) steels are oriented to applications where high operating temperatures and good corrosion resistance is paramount. However, their use is compromised by their fracture toughness, which is lower than other competing ferritic-martenstic steels. In addition, the route required in manufacturing these alloys generates texture in the material, which induces a strong anisotropy in properties.
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