Publications by authors named "J C Pettersen"
G-protein-coupled receptors (GPCRs) represent one of the largest classes of therapeutic targets. However, developing successful therapeutics to target GPCRs is a challenging endeavor, with many molecules failing during in vivo clinical trials due to a lack of efficacy. The in vitro identification of drug-target residence time (1/k) has been suggested to improve predictions of in vivo success.
View Article and Find Full Text PDFBackground And Objectives: Sex and gender are important topics of increasing interest in aging and dementia research. Few studies have jointly examined sex (as a biological attribute) and gender (as a sociocultural and behavioral characteristic) within a single study. We explored a novel data mining approach to include both sex and gender as potentially related influences in memory aging research.
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- A study examined eating problems among adolescents during the pandemic compared to before, using data from 22,706 14-16-year-olds over six years.
- Results indicated that while all adolescents showed an increase in eating problems over time, the pandemic uniquely affected girls, who reported higher levels of dieting and body dissatisfaction during this period.
- The findings emphasize the need to address gender-specific issues related to eating problems and suggest that factors like screen time and mental distress may have worsened during the pandemic.
Purpose: Marine vertebrate populations have halved in the past decades, and invasive species are a major driver for this loss. While many model the spread of invasive species, a model to assess impacts of marine invasions, after introduction, has hitherto been missing. We present the first regionalized effect factors for marine invasions.
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- Adolescence is a crucial time when mental health issues like anxiety and depression can start to appear, and the COVID-19 pandemic's strict public health measures may have worsened these conditions for teens.* -
- The study investigated how public health restrictions and experiences with quarantine impacted mental distress in a group of 7,787 Norwegian adolescents aged 16 to 18 from April 2020 to February 2021.* -
- Findings showed that higher stringency of public health measures and recent or frequent quarantines were linked to increased mental distress, with no significant moderating effects from factors like sex or pre-existing mental health issues.*